Cardiolipin deficiency in Barth syndrome is not associated with increased superoxide/H(2)O(2) production in heart and skeletal muscle mitochondria

Barth syndrome (BTHS) is a rare X‐linked genetic disorder caused by mutations in the gene encoding the transacylase tafazzin and characterized by loss of cardiolipin and severe cardiomyopathy. Mitochondrial oxidants have been implicated in the cardiomyopathy in BTHS. Eleven mitochondrial sites produ...

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Detalles Bibliográficos
Autores principales: Goncalves, Renata L. S., Schlame, Michael, Bartelt, Alexander, Brand, Martin D., Hotamışlıgil, Gökhan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894513/
https://www.ncbi.nlm.nih.gov/pubmed/33112430
http://dx.doi.org/10.1002/1873-3468.13973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894513/
https://www.ncbi.nlm.nih.gov/pubmed/33112430
http://dx.doi.org/10.1002/1873-3468.13973

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