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Multivalent, Stabilized Mannose‐6‐Phosphates for the Targeted Delivery of Toll‐Like Receptor Ligands and Peptide Antigens

Mannose‐6‐phosphate (M6P) is recognized by the mannose‐6‐phosphate receptor and plays an important role in the transport of cargo to the endosomes, making it an attractive tool to improve endosomal trafficking of vaccines. We describe herein the assembly of peptide antigen conjugates carrying cluste...

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Detalles Bibliográficos
Autores principales: Reintjens, Niels R. M., Tondini, Elena, Vis, Christopher, McGlinn, Toroa, Meeuwenoord, Nico J., Hogervorst, Tim P., Overkleeft, Herman S., Filippov, Dmitri V., van der Marel, Gijsbert A., Ossendorp, Ferry, Codée, Jeroen D. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894537/
https://www.ncbi.nlm.nih.gov/pubmed/32864819
http://dx.doi.org/10.1002/cbic.202000538