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C‐Terminal Tag Location Hampers in Vitro Profiling of OGT Peptide Substrates by mRNA Display
O‐GlcNAc transferase (OGT) is the only enzyme that catalyzes the post‐translational modification of proteins at Ser/Thr with a single β‐N‐acetylglucosamine (O‐GlcNAcylation). Its activity has been associated with chronic diseases such as cancer, diabetes and neurodegenerative disease. Although numer...
Autores principales: | Shi, Jie, Sharif, Suhela, Balsollier, Cyril, Ruijtenbeek, Rob, Pieters, Roland J., Jongkees, Seino A. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894566/ https://www.ncbi.nlm.nih.gov/pubmed/33022805 http://dx.doi.org/10.1002/cbic.202000624 |
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