Structure‐Activity Relationships of Benzamides and Isoindolines Designed as SARS‐CoV Protease Inhibitors Effective against SARS‐CoV‐2

Inhibition of coronavirus (CoV)‐encoded papain‐like cysteine proteases (PL(pro)) represents an attractive strategy to treat infections by these important human pathogens. Herein we report on structure‐activity relationships (SAR) of the noncovalent active‐site directed inhibitor (R)‐5‐amino‐2‐methyl...

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Detalles Bibliográficos
Autores principales: Welker, Armin, Kersten, Christian, Müller, Christin, Madhugiri, Ramakanth, Zimmer, Collin, Müller, Patrick, Zimmermann, Robert, Hammerschmidt, Stefan, Maus, Hannah, Ziebuhr, John, Sotriffer, Christoph, Schirmeister, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894572/
https://www.ncbi.nlm.nih.gov/pubmed/32930481
http://dx.doi.org/10.1002/cmdc.202000548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894572/
https://www.ncbi.nlm.nih.gov/pubmed/32930481
http://dx.doi.org/10.1002/cmdc.202000548

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