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Use of dual-transfection for programmed death cell protein 1 disruption mediated by CRISPR-Cas9 in human peripheral blood mononuclear cells

OBJECTIVE(S): Checkpoint blocking is considered a revolutionary method in cancer treatment. This method eliminates cancer cells by maintaining the sensitivity of immune cells. Today, cell therapy through checkpoint blocking is known as the most efficient method of cancer treatment. The programmed ce...

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Detalles Bibliográficos
Autores principales: Alambeladi, SeyedAli, Hosseiny, SeyedEbrahim, Jafarinia, Mojtaba, Dianatpour, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894638/
https://www.ncbi.nlm.nih.gov/pubmed/33643569
http://dx.doi.org/10.22038/ijbms.2020.48566.11146