Imaging the mechanisms of anti-CD20 therapy in vivo uncovers spatiotemporal bottlenecks in antibody-dependent phagocytosis

Anti-CD20 antibody (mAb) represents an effective strategy for the treatment of B cell malignancies, possibly involving complement activity, antibody-dependent cellular cytotoxicity and phagocytosis (ADP). While ADP by Kupffer cells deplete circulating tumors, mechanisms targeting non-circulating tum...

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Detalles Bibliográficos
Autores principales: Grandjean, Capucine L., Garcia, Zacarias, Lemaître, Fabrice, Bréart, Béatrice, Bousso, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895428/
https://www.ncbi.nlm.nih.gov/pubmed/33608271
http://dx.doi.org/10.1126/sciadv.abd6167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895428/
https://www.ncbi.nlm.nih.gov/pubmed/33608271
http://dx.doi.org/10.1126/sciadv.abd6167

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