The one-carbon pool controls mitochondrial energy metabolism via complex I and iron-sulfur clusters

Induction of the one-carbon cycle is an early hallmark of mitochondrial dysfunction and cancer metabolism. Vital intermediary steps are localized to mitochondria, but it remains unclear how one-carbon availability connects to mitochondrial function. Here, we show that the one-carbon metabolite and m...

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Detalles Bibliográficos
Autores principales: Schober, Florian A., Moore, David, Atanassov, Ilian, Moedas, Marco F., Clemente, Paula, Végvári, Ákos, Fissi, Najla El, Filograna, Roberta, Bucher, Anna-Lena, Hinze, Yvonne, The, Matthew, Hedman, Erik, Chernogubova, Ekaterina, Begzati, Arjana, Wibom, Rolf, Jain, Mohit, Nilsson, Roland, Käll, Lukas, Wedell, Anna, Freyer, Christoph, Wredenberg, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895438/
https://www.ncbi.nlm.nih.gov/pubmed/33608280
http://dx.doi.org/10.1126/sciadv.abf0717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895438/
https://www.ncbi.nlm.nih.gov/pubmed/33608280
http://dx.doi.org/10.1126/sciadv.abf0717

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