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PCSK9 mediates the oxidative low-density lipoprotein-induced pyroptosis of vascular endothelial cells via the UQCRC1/ROS pathway

The present study aimed to explore the role and mechanisms of proprotein convertase subtilisin/kexin type 9 (PCSK9) in the oxidized low-density lipoprotein (oxLDL)-induced pyroptosis of vascular endothelial cells. For this purpose, human umbilical vein endothelial cells (HUVECs) were incubated with...

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Detalles Bibliográficos
Autores principales: Zeng, Junfa, Tao, Jun, Xi, Linzhen, Wang, Zuo, Liu, Lushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895513/
https://www.ncbi.nlm.nih.gov/pubmed/33576442
http://dx.doi.org/10.3892/ijmm.2021.4886