Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Diabetic nephropathy (DN) is the primary cause of end-stage renal disease, which is closely associated with dysfunction of the podocytes, the main component of the glomerular filtration membrane; however, the exact underlying mechanism is unknown. Polyamines, including spermine, spermidine and putre...

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Detalles Bibliográficos
Autores principales: Zhang, Xinying, Zhang, Li, Chen, Zhe, Li, Siwei, Che, Bingbing, Wang, Ningning, Chen, Junting, Xu, Changqing, Wei, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895520/
https://www.ncbi.nlm.nih.gov/pubmed/33537831
http://dx.doi.org/10.3892/ijmm.2021.4860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895520/
https://www.ncbi.nlm.nih.gov/pubmed/33537831
http://dx.doi.org/10.3892/ijmm.2021.4860

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