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Pre-existing bilayer stresses modulate triglyceride accumulation in the ER versus lipid droplets

Cells store energy in the form of neutral lipids (NLs) packaged into micrometer-sized organelles named lipid droplets (LDs). These structures emerge from the endoplasmic reticulum (ER) at sites marked by the protein seipin, but the mechanisms regulating their biogenesis remain poorly understood. Usi...

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Detalles Bibliográficos
Autores principales: Zoni, Valeria, Khaddaj, Rasha, Campomanes, Pablo, Thiam, Abdou Rachid, Schneiter, Roger, Vanni, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895522/
https://www.ncbi.nlm.nih.gov/pubmed/33522484
http://dx.doi.org/10.7554/eLife.62886