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Loss of cortical control over the descending pain modulatory system determines the development of the neuropathic pain state in rats
The loss of descending inhibitory control is thought critical to the development of chronic pain but what causes this loss in function is not well understood. We have investigated the dynamic contribution of prelimbic cortical neuronal projections to the periaqueductal grey (PrL-P) to the developmen...
Autores principales: | Drake, Robert AR, Steel, Kenneth A, Apps, Richard, Lumb, Bridget M, Pickering, Anthony E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895525/ https://www.ncbi.nlm.nih.gov/pubmed/33555256 http://dx.doi.org/10.7554/eLife.65156 |
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