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Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription
The Hippo (Hpo) pathway regulates tissue growth in many animals. Multiple upstream components promote Hpo pathway activity, but the organization of these different inputs, the degree of crosstalk between them, and whether they are regulated in a distinct manner is not well understood. Kibra (Kib) ac...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895526/ https://www.ncbi.nlm.nih.gov/pubmed/33555257 http://dx.doi.org/10.7554/eLife.62326 |