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A universal protocol for isolating retinal ON bipolar cells across species via fluorescence-activated cell sorting

Inherited retinal dystrophies (IRDs) are characterized by progressive degeneration and loss of light-sensing photoreceptors. The most promising therapeutic approach for IRDs is gene supplementation therapy using viral vectors, which requires the presence of viable photoreceptors at the time of inter...

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Detalles Bibliográficos
Autores principales: Murenu, Elisa, Pavlou, Marina, Richter, Lisa, Rapti, Kleopatra, Just, Sabrina, Cehajic-Kapetanovic, Jasmina, Tafrishi, Neda, Hayes, Andrew, Scholey, Rachel, Lucas, Robert, Büning, Hildegard, Grimm, Dirk, Michalakis, Stylianos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895692/
https://www.ncbi.nlm.nih.gov/pubmed/33665228
http://dx.doi.org/10.1016/j.omtm.2021.01.011