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Core 2 β1,6-N-acetylglucosaminyltransferases accelerate the escape of choriocarcinoma from natural killer cell immunity

Hyperglycosylated human chorionic gonadotropin (H-hCG) is secreted from choriocarcinoma and contains a core2 O-glycan formed by core2 β1,6-N-acetylglucosaminyl transferase (C2GnT). Choriocarcinoma is considered immunogenic as it is gestational and contains paternal chromosomal components. Here we ex...

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Detalles Bibliográficos
Autores principales: Nakamura, Kenichi, Niimi, Kaoru, Yamamoto, Eiko, Ikeda, Yoshiki, Nishino, Kimihiro, Suzuki, Shiro, Kajiyama, Hiroaki, Kikkawa, Fumitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895715/
https://www.ncbi.nlm.nih.gov/pubmed/33644424
http://dx.doi.org/10.1016/j.bbrep.2021.100951