A data-driven computational model enables integrative and mechanistic characterization of dynamic macrophage polarization

Macrophages are highly plastic immune cells that dynamically integrate microenvironmental signals to shape their own functional phenotypes, a process known as polarization. Here we develop a large-scale mechanistic computational model that for the first time enables a systems-level characterization,...

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Detalles Bibliográficos
Autores principales: Zhao, Chen, Medeiros, Thalyta X., Sové, Richard J., Annex, Brian H., Popel, Aleksander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895754/
https://www.ncbi.nlm.nih.gov/pubmed/33659877
http://dx.doi.org/10.1016/j.isci.2021.102112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895754/
https://www.ncbi.nlm.nih.gov/pubmed/33659877
http://dx.doi.org/10.1016/j.isci.2021.102112

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