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Distinct functions of transforming growth factor-β signaling in c-MYC driven hepatocellular carcinoma initiation and progression

Dysregulation of transforming growth factor-beta (TGFβ) signaling has been implicated in liver carcinogenesis with both tumor promoting and inhibiting activities. Activation of the c-MYC protooncogene is another critical genetic event in hepatocellular carcinoma (HCC). However, the precise functiona...

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Detalles Bibliográficos
Autores principales: Wang, Haichuan, Wang, Pan, Xu, Meng, Song, Xinhua, Wu, Hong, Evert, Matthias, Calvisi, Diego F., Zeng, Yong, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895828/
https://www.ncbi.nlm.nih.gov/pubmed/33608500
http://dx.doi.org/10.1038/s41419-021-03488-z