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The function and regulation of TET2 in innate immunity and inflammation

TET2, a member of ten-eleven translocation (TET) family as α-ketoglutarate- and Fe(2+)-dependent dioxygenase catalyzing the iterative oxidation of 5-methylcytosine (5mC), has been widely recognized to be an important regulator for normal hematopoiesis especially myelopoiesis. Mutation and dysregulat...

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Detalles Bibliográficos
Autores principales: Cong, Boyi, Zhang, Qian, Cao, Xuetao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895883/
https://www.ncbi.nlm.nih.gov/pubmed/33085059
http://dx.doi.org/10.1007/s13238-020-00796-6