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The function and regulation of TET2 in innate immunity and inflammation
TET2, a member of ten-eleven translocation (TET) family as α-ketoglutarate- and Fe(2+)-dependent dioxygenase catalyzing the iterative oxidation of 5-methylcytosine (5mC), has been widely recognized to be an important regulator for normal hematopoiesis especially myelopoiesis. Mutation and dysregulat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895883/ https://www.ncbi.nlm.nih.gov/pubmed/33085059 http://dx.doi.org/10.1007/s13238-020-00796-6 |