Therapeutic silencing miR-146b-5p improves cardiac remodeling in a porcine model of myocardial infarction by modulating the wound reparative phenotype

Fibrotic remodeling is an adverse consequence of immune response-driven phenotypic modulation of cardiac cells following myocardial infarction (MI). MicroRNA-146b (miR-146b) is an active regulator of immunomodulation, but its function in the cardiac inflammatory cascade and its clinical implication...

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Detalles Bibliográficos
Autores principales: Liao, Yiteng, Li, Hao, Cao, Hao, Dong, Yun, Gao, Lei, Liu, Zhongmin, Ge, Junbo, Zhu, Hongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895884/
https://www.ncbi.nlm.nih.gov/pubmed/32845445
http://dx.doi.org/10.1007/s13238-020-00750-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895884/
https://www.ncbi.nlm.nih.gov/pubmed/32845445
http://dx.doi.org/10.1007/s13238-020-00750-6

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