Distinct Ring1b complexes defined by DEAD-box helicases and EMT transcription factors synergistically enhance E-cadherin silencing in breast cancer

Ring1b is a core subunit of polycomb repressive complex 1 (PRC1) and is essential in several high-risk cancers. However, the epigenetic mechanism of Ring1b underlying breast cancer malignancy is poorly understood. In this study, we showed increased expression of Ring1b promoted metastasis by weakeni...

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Detalles Bibliográficos
Autores principales: Wang, Yawei, Sun, Yingying, Shang, Chao, Chen, Lili, Chen, Hongyu, Wang, Dake, Zeng, Xianlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895950/
https://www.ncbi.nlm.nih.gov/pubmed/33608512
http://dx.doi.org/10.1038/s41419-021-03491-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895950/
https://www.ncbi.nlm.nih.gov/pubmed/33608512
http://dx.doi.org/10.1038/s41419-021-03491-4

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