Elevated inflammatory responses and targeted therapeutic intervention in a preclinical mouse model of ataxia-telangiectasia lung disease

Ataxia-telangiectasia (A-T) is an autosomal recessive, multisystem disorder characterized by cerebellar degeneration, cancer predisposition, and immune system defects. A major cause of mortality in A-T patients is severe pulmonary disease; however, the underlying causes of the lung complications are...

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Detalles Bibliográficos
Autores principales: Saunders, Rudel A., Michniacki, Thomas F., Hames, Courtney, Moale, Hilary A., Wilke, Carol, Kuo, Molly E., Nguyen, Johnathan, Hartlerode, Andrea J., Moore, Bethany B., Sekiguchi, JoAnn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895952/
https://www.ncbi.nlm.nih.gov/pubmed/33608602
http://dx.doi.org/10.1038/s41598-021-83531-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895952/
https://www.ncbi.nlm.nih.gov/pubmed/33608602
http://dx.doi.org/10.1038/s41598-021-83531-3

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