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Allosteric Pathways Originating at Cysteine Residues in Regulators of G-Protein Signaling Proteins
Regulators of G-protein signaling (RGS) proteins play a central role in modulating signaling via G-protein coupled receptors (GPCRs). Specifically, RGS proteins bind to activated Gα subunits in G-proteins, accelerate the GTP hydrolysis, and thereby rapidly dampen GPCR signaling. Therefore, covalent...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Biophysical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895990/ https://www.ncbi.nlm.nih.gov/pubmed/33347886 http://dx.doi.org/10.1016/j.bpj.2020.12.010 |