Modulating the unfolded protein response with ONC201 to impact on radiation response in prostate cancer cells

Prostate cancer (PCa) is the most common non-cutaneous cancer in men and a notable cause of cancer mortality when it metastasises. The unfolded protein response (UPR) can be cytoprotective but when acutely activated can lead to cell death. In this study, we sought to enhance the acute activation of...

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Detalles Bibliográficos
Autores principales: Amoroso, Francesca, Glass, Kimberley, Singh, Reema, Liberal, Francisco, Steele, Rebecca E., Maguire, Sarah, Tarapore, Rohinton, Allen, Joshua E., Van Schaeybroeck, Sandra, Butterworth, Karl T., Prise, Kevin, O’Sullivan, Joe M., Jain, Suneil, Waugh, David J., Mills, Ian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896060/
https://www.ncbi.nlm.nih.gov/pubmed/33608585
http://dx.doi.org/10.1038/s41598-021-83215-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896060/
https://www.ncbi.nlm.nih.gov/pubmed/33608585
http://dx.doi.org/10.1038/s41598-021-83215-y

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