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AT(1) receptor blocker, but not an ACE inhibitor, prevents kidneys from hypoperfusion during congestive heart failure in normotensive and hypertensive rats

To provide novel insights into the pathogenesis of heart failure-induced renal dysfunction, we compared the effects of ACE inhibitor (ACEi) and AT(1) receptor blocker (ARB) on systemic and kidney hemodynamics during heart failure in normotensive HanSD and hypertensive transgenic (TGR) rats. High-out...

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Detalles Bibliográficos
Autores principales: Kratky, Vojtech, Vanourkova, Zdenka, Sykora, Matus, Bacova, Barbara Szeiffova, Hruskova, Zdenka, Kikerlova, Sona, Huskova, Zuzana, Kopkan, Libor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896062/
https://www.ncbi.nlm.nih.gov/pubmed/33608612
http://dx.doi.org/10.1038/s41598-021-83906-6