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Deep learning the collisional cross sections of the peptide universe from a million experimental values

The size and shape of peptide ions in the gas phase are an under-explored dimension for mass spectrometry-based proteomics. To investigate the nature and utility of the peptide collisional cross section (CCS) space, we measure more than a million data points from whole-proteome digests of five organ...

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Detalles Bibliográficos
Autores principales: Meier, Florian, Köhler, Niklas D., Brunner, Andreas-David, Wanka, Jean-Marc H., Voytik, Eugenia, Strauss, Maximilian T., Theis, Fabian J., Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896072/
https://www.ncbi.nlm.nih.gov/pubmed/33608539
http://dx.doi.org/10.1038/s41467-021-21352-8