Cargando…

Deletion of FGF9 in GABAergic neurons causes epilepsy

Fibroblast growth factor 9 (FGF9) has long been assumed to modulate multiple biological processes, yet very little is known about the impact of FGF9 on neurodevelopment. Herein, we found that loss of Fgf9 in olig1 progenitor cells induced epilepsy in mice, with pathological changes in the cortex. Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Moran, Cui, Can, Song, Xueqin, Jia, Lijing, Li, Duan, Wang, Xiuli, Dong, Hui, Ma, Yanqin, Liu, Yaling, Cui, Zhiqiang, Yi, Le, Li, Zhongyao, Bi, Yue, Li, Yuanyuan, Liu, Yakun, Duan, Weisong, Li, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896082/
https://www.ncbi.nlm.nih.gov/pubmed/33608505
http://dx.doi.org/10.1038/s41419-021-03478-1