GBP5 drives malignancy of glioblastoma via the Src/ERK1/2/MMP3 pathway

Guanylate binding proteins (GBPs), a family of interferon-inducible large GTPase, play a pivotal role in cell-autonomous immunity and tumor malignant transformation. Glioblastoma (GBM) is the most prevalent and lethal primary brain tumor in adults. Here we show that GBP5 was highly expressed in GBM...

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Detalles Bibliográficos
Autores principales: Yu, Xiaoting, Jin, Jing, Zheng, Yanwen, Zhu, Hua, Xu, Hui, Ma, Jun, Lan, Qing, Zhuang, Zhixiang, Chen, Clark C., Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896088/
https://www.ncbi.nlm.nih.gov/pubmed/33608513
http://dx.doi.org/10.1038/s41419-021-03492-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896088/
https://www.ncbi.nlm.nih.gov/pubmed/33608513
http://dx.doi.org/10.1038/s41419-021-03492-3

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