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Glycogen synthase kinase-3β inhibitor SB216763 promotes DNA repair in ischemic retinal neurons

Glycogen synthase kinase-3β (GSK-3β) has been shown to attenuate DNA damage in nerve cells, thereby enhancing neuronal survival under pathological conditions; however, the underlying mechanism remains unclear. An in vitro serum-starvation retinal neuron model and in vivo ischemia/reperfusion retina...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Lai, Zhi-Peng, Chen, Pei, Ying, Yang, Zhuang, Jing, Yu, Ke-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896226/
https://www.ncbi.nlm.nih.gov/pubmed/32859805
http://dx.doi.org/10.4103/1673-5374.290913