Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP

The RNA polymerase inhibitor favipiravir is currently in clinical trials as a treatment for infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), despite limited information about the molecular basis for its activity. Here we report the structure of favipiravir ribonucleoside...

Descripción completa

Detalles Bibliográficos
Autores principales: Naydenova, Katerina, Muir, Kyle W., Wu, Long-Fei, Zhang, Ziguo, Coscia, Francesca, Peet, Mathew J., Castro-Hartmann, Pablo, Qian, Pu, Sader, Kasim, Dent, Kyle, Kimanius, Dari, Sutherland, John D., Löwe, Jan, Barford, David, Russo, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896311/
https://www.ncbi.nlm.nih.gov/pubmed/33526596
http://dx.doi.org/10.1073/pnas.2021946118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896311/
https://www.ncbi.nlm.nih.gov/pubmed/33526596
http://dx.doi.org/10.1073/pnas.2021946118

Ejemplares similares