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Thyrotropin N-glycosylation and Glycan Composition in Severe Primary Hypothyroidism

CONTEXT: In severe primary hypothyroidism (sPH), the serum thyrotropin (TSH) levels are elevated with an increased degree of sialylation. The circulating TSH comprises 2 different TSH glycoforms: TSHdi with 2 and TSHtri with 3 N-glycans and methods have developed to determine their contents of anion...

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Detalles Bibliográficos
Autores principales: Wide, Leif, Eriksson, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896355/
https://www.ncbi.nlm.nih.gov/pubmed/33644618
http://dx.doi.org/10.1210/jendso/bvab006