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Thyrotropin N-glycosylation and Glycan Composition in Severe Primary Hypothyroidism
CONTEXT: In severe primary hypothyroidism (sPH), the serum thyrotropin (TSH) levels are elevated with an increased degree of sialylation. The circulating TSH comprises 2 different TSH glycoforms: TSHdi with 2 and TSHtri with 3 N-glycans and methods have developed to determine their contents of anion...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896355/ https://www.ncbi.nlm.nih.gov/pubmed/33644618 http://dx.doi.org/10.1210/jendso/bvab006 |