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Circular RNA circVAPA promotes chemotherapy drug resistance in gastric cancer progression by regulating miR-125b-5p/STAT3 axis

BACKGROUND: Gastric cancer (GC) is a prevalent malignancy, leading to a high incidence of cancer-associated death. Cisplatin (DDP)-based chemotherapy is the principal therapy for clinical GC treatment, but DDP resistance is a severe clinical challenge and the mechanism remains poorly understood. Cir...

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Detalles Bibliográficos
Autores principales: Deng, Peng, Sun, Ming, Zhao, Wen-Yan, Hou, Bin, Li, Kai, Zhang, Tao, Gu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896438/
https://www.ncbi.nlm.nih.gov/pubmed/33642823
http://dx.doi.org/10.3748/wjg.v27.i6.487