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Docking-based virtual screening studies aiming at the covalent inhibition of SARS-CoV-2 M(Pro) by targeting the cysteine 145

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the COVID-19 which has infected millions of people worldwide. The main protease of SARS-CoV-2 (M(Pro)) has been recognized as a key target for the development of antiviral compounds. Taking advantage of the X-ray cry...

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Detalles Bibliográficos
Autores principales: Soulère, Laurent, Barbier, Thibaut, Queneau, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896498/
https://www.ncbi.nlm.nih.gov/pubmed/33677227
http://dx.doi.org/10.1016/j.compbiolchem.2021.107463