Differential combination immunotherapy requirements for inflamed (warm) tumors versus T cell excluded (cool) tumors: engage, expand, enable, and evolve

BACKGROUND: Different types of tumors have varying susceptibility to immunotherapy and hence require different treatment strategies; these cover a spectrum ranging from ‘hot’ tumors or those with high mutational burden and immune infiltrates that are more amenable to targeting to ‘cold’ tumors that...

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Detalles Bibliográficos
Autores principales: Fabian, Kellsye P, Padget, Michelle R, Fujii, Rika, Schlom, Jeffrey, Hodge, James W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896589/
https://www.ncbi.nlm.nih.gov/pubmed/33602696
http://dx.doi.org/10.1136/jitc-2020-001691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896589/
https://www.ncbi.nlm.nih.gov/pubmed/33602696
http://dx.doi.org/10.1136/jitc-2020-001691

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