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Salvianolic Acid B Protects Intervertebral Discs from Oxidative Stress-Induced Degeneration via Activation of the JAK2/STAT3 Signaling Pathway

OBJECTIVE: To evaluate the influence of salvianolic acid B (SAB), an antioxidant derived from Danshen, on intervertebral disc degeneration (IDD) and its possible molecular mechanisms. METHODS: Sixty adult rats were randomly grouped (control, IDD, and SAB IDD groups). IDD was induced using needle pun...

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Detalles Bibliográficos
Autores principales: Dai, Shouqian, Liang, Ting, Shi, Xiu, Luo, Zongping, Yang, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896869/
https://www.ncbi.nlm.nih.gov/pubmed/33628378
http://dx.doi.org/10.1155/2021/6672978