Secreted frizzled-related protein 2: a key player in noncanonical Wnt signaling and tumor angiogenesis

Secreted frizzled-related proteins (SFRP) are glycoproteins containing a so-called frizzled-like cysteine-rich domain. This domain enables them to bind to Wnt ligands or frizzled (FzD) receptors, making potent regulators of Wnt signaling. As Wnt signaling is often altered in cancer, it is not surpri...

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Detalles Bibliográficos
Autores principales: van Loon, Karlijn, Huijbers, Elisabeth J. M., Griffioen, Arjan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Non-Thematic Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897195/
https://www.ncbi.nlm.nih.gov/pubmed/33140138
http://dx.doi.org/10.1007/s10555-020-09941-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897195/
https://www.ncbi.nlm.nih.gov/pubmed/33140138
http://dx.doi.org/10.1007/s10555-020-09941-3

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