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Secreted frizzled-related protein 2: a key player in noncanonical Wnt signaling and tumor angiogenesis
Secreted frizzled-related proteins (SFRP) are glycoproteins containing a so-called frizzled-like cysteine-rich domain. This domain enables them to bind to Wnt ligands or frizzled (FzD) receptors, making potent regulators of Wnt signaling. As Wnt signaling is often altered in cancer, it is not surpri...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897195/ https://www.ncbi.nlm.nih.gov/pubmed/33140138 http://dx.doi.org/10.1007/s10555-020-09941-3 |