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High‐ and low‐molecular‐weight chitosan act as adjuvants during single‐dose influenza A virus protein vaccination through distinct mechanisms

The investigation of new adjuvants is essential for the development of efficacious vaccines. Chitosan (CS), a derivative of chitin, has been shown to act as an adjuvant, improving vaccine‐induced immune responses. However, the effect of CS molecular weight (MW) on this adjuvanticity has not been inv...

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Detalles Bibliográficos
Autores principales: Lampe, Anna T., Farris, Eric J., Brown, Deborah M., Pannier, Angela K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897297/
https://www.ncbi.nlm.nih.gov/pubmed/33289090
http://dx.doi.org/10.1002/bit.27647