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The role of m6A modification in the biological functions and diseases

N(6)-methyladenosine (m6A) is the most prevalent, abundant and conserved internal cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells. m6A modification is modified by the m6A methyltransferases, or writers, such as METTL3/14/16, RBM15/15B, ZC3H3, VIRMA, CBLL1...

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Detalles Bibliográficos
Autores principales: Jiang, Xiulin, Liu, Baiyang, Nie, Zhi, Duan, Lincan, Xiong, Qiuxia, Jin, Zhixian, Yang, Cuiping, Chen, Yongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897327/
https://www.ncbi.nlm.nih.gov/pubmed/33611339
http://dx.doi.org/10.1038/s41392-020-00450-x