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Identification and validation of a miRNA-related expression signature for tumor mutational burden in colorectal cancer
BACKGROUND: Tumor mutational burden (TMB) is a promising predictor, which could stratify colorectal cancer (CRC) patients based on the response to immune checkpoint inhibitors (ICIs). MicroRNAs (miRNAs) act as the key regulators of anti-cancer immune response. However, the relationship between TMB a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897378/ https://www.ncbi.nlm.nih.gov/pubmed/33610190 http://dx.doi.org/10.1186/s12957-021-02137-1 |