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Identification and validation of a miRNA-related expression signature for tumor mutational burden in colorectal cancer

BACKGROUND: Tumor mutational burden (TMB) is a promising predictor, which could stratify colorectal cancer (CRC) patients based on the response to immune checkpoint inhibitors (ICIs). MicroRNAs (miRNAs) act as the key regulators of anti-cancer immune response. However, the relationship between TMB a...

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Detalles Bibliográficos
Autores principales: Xu, Lijun, Zheng, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897378/
https://www.ncbi.nlm.nih.gov/pubmed/33610190
http://dx.doi.org/10.1186/s12957-021-02137-1