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Interleukin-1β mediates alterations in mitochondrial fusion/fission proteins and memory impairment induced by amyloid-β oligomers

BACKGROUND: The lack of effective treatments for Alzheimer’s disease (AD) reflects an incomplete understanding of disease mechanisms. Alterations in proteins involved in mitochondrial dynamics, an essential process for mitochondrial integrity and function, have been reported in AD brains. Impaired m...

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Detalles Bibliográficos
Autores principales: Batista, Andre F., Rody, Tayná, Forny-Germano, Leticia, Cerdeiro, Suzana, Bellio, Maria, Ferreira, Sergio T., Munoz, Douglas P., De Felice, Fernanda G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897381/
https://www.ncbi.nlm.nih.gov/pubmed/33612100
http://dx.doi.org/10.1186/s12974-021-02099-x