Tissue plasminogen activator worsens experimental autoimmune encephalomyelitis by complementary actions on lymphoid and myeloid cell responses

BACKGROUND: Tissue plasminogen activator (tPA) is a serine protease involved in fibrinolysis. It is released by endothelial cells, but also expressed by neurons and glial cells in the central nervous system (CNS). Interestingly, this enzyme also contributes to pathological processes in the CNS such...

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Detalles Bibliográficos
Autores principales: Hélie, Pauline, Camacho-Toledano, Celia, Lesec, Léonie, Seillier, Célia, Miralles, Antonio J., Ortega, Maria Cristina, Guérit, Sylvaine, Lebas, Héloïse, Bardou, Isabelle, Vila-del Sol, Virginia, Vivien, Denis, Le Mauff, Brigitte, Clemente, Diego, Docagne, Fabian, Toutirais, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897384/
https://www.ncbi.nlm.nih.gov/pubmed/33610187
http://dx.doi.org/10.1186/s12974-021-02102-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897384/
https://www.ncbi.nlm.nih.gov/pubmed/33610187
http://dx.doi.org/10.1186/s12974-021-02102-5

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