The ORF8 protein of SARS-CoV-2 induced endoplasmic reticulum stress and mediated immune evasion by antagonizing production of interferon beta

The open reading frame 8 (orf8) is an accessory protein of SARS-CoV-2. It has 121 amino acids with two genotypes, orf8L and orf8S. In this study, we overexpressed the orf8L and orf8S of SARS-CoV-2 as well as the orf8b of SARS-CoV to investigate their roles in the regulation of endoplasmic reticulum...

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Detalles Bibliográficos
Autores principales: Rashid, Farooq, Dzakah, Emmanuel Enoch, Wang, Haiying, Tang, Shixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897408/
https://www.ncbi.nlm.nih.gov/pubmed/33626380
http://dx.doi.org/10.1016/j.virusres.2021.198350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897408/
https://www.ncbi.nlm.nih.gov/pubmed/33626380
http://dx.doi.org/10.1016/j.virusres.2021.198350

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