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A supernumerary designer chromosome for modular in vivo pathway assembly in Saccharomyces cerevisiae
The construction of microbial cell factories for sustainable production of chemicals and pharmaceuticals requires extensive genome engineering. Using Saccharomyces cerevisiae, this study proposes synthetic neochromosomes as orthogonal expression platforms for rewiring native cellular processes and i...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897487/ https://www.ncbi.nlm.nih.gov/pubmed/33423048 http://dx.doi.org/10.1093/nar/gkaa1167 |