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The solution structures of higher-order human telomere G-quadruplex multimers

Human telomeres contain the repeat DNA sequence 5′-d(TTAGGG), with duplex regions that are several kilobases long terminating in a 3′ single-stranded overhang. The structure of the single-stranded overhang is not known with certainty, with disparate models proposed in the literature. We report here...

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Detalles Bibliográficos
Autores principales: Monsen, Robert C, Chakravarthy, Srinivas, Dean, William L, Chaires, Jonathan B, Trent, John O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897503/
https://www.ncbi.nlm.nih.gov/pubmed/33469644
http://dx.doi.org/10.1093/nar/gkaa1285