Evidence for multi-copy Mega-NUMTs in the human genome

The maternal mode of mitochondrial DNA (mtDNA) inheritance is central to human genetics. Recently, evidence for bi-parental inheritance of mtDNA was claimed for individuals of three pedigrees that suffered mitochondrial disorders. We sequenced mtDNA using both direct Sanger and Massively Parallel Se...

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Detalles Bibliográficos
Autores principales: Lutz-Bonengel, Sabine, Niederstätter, Harald, Naue, Jana, Koziel, Rafal, Yang, Fengtang, Sänger, Timo, Huber, Gabriela, Berger, Cordula, Pflugradt, René, Strobl, Christina, Xavier, Catarina, Volleth, Marianne, Weiß, Sandra Carina, Irwin, Jodi A, Romsos, Erica L, Vallone, Peter M, Ratzinger, Gudrun, Schmuth, Matthias, Jansen-Dürr, Pidder, Liehr, Thomas, Lichter, Peter, Parsons, Thomas J, Pollak, Stefan, Parson, Walther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897518/
https://www.ncbi.nlm.nih.gov/pubmed/33450006
http://dx.doi.org/10.1093/nar/gkaa1271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897518/
https://www.ncbi.nlm.nih.gov/pubmed/33450006
http://dx.doi.org/10.1093/nar/gkaa1271

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