Evidence for multi-copy Mega-NUMTs in the human genome

The maternal mode of mitochondrial DNA (mtDNA) inheritance is central to human genetics. Recently, evidence for bi-parental inheritance of mtDNA was claimed for individuals of three pedigrees that suffered mitochondrial disorders. We sequenced mtDNA using both direct Sanger and Massively Parallel Se...

Descripción completa

Detalles Bibliográficos
Autores principales: Lutz-Bonengel, Sabine, Niederstätter, Harald, Naue, Jana, Koziel, Rafal, Yang, Fengtang, Sänger, Timo, Huber, Gabriela, Berger, Cordula, Pflugradt, René, Strobl, Christina, Xavier, Catarina, Volleth, Marianne, Weiß, Sandra Carina, Irwin, Jodi A, Romsos, Erica L, Vallone, Peter M, Ratzinger, Gudrun, Schmuth, Matthias, Jansen-Dürr, Pidder, Liehr, Thomas, Lichter, Peter, Parsons, Thomas J, Pollak, Stefan, Parson, Walther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897518/
https://www.ncbi.nlm.nih.gov/pubmed/33450006
http://dx.doi.org/10.1093/nar/gkaa1271

Ejemplares similares

Ejemplares similares