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Bach2 Deficiency Promotes Intestinal Epithelial Regeneration by Accelerating DNA Repair in Intestinal Stem Cells

Epithelial regeneration is critical for barrier maintenance and organ function after intestinal injury, although the repair mechanisms are unclear. Here, we found that Bach2 deficiency promotes intestinal epithelial cell proliferation during homeostasis. Moreover, genetic inactivation of Bach2 in mo...

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Detalles Bibliográficos
Autores principales: Li, Yuanchuang, Rao, Xinxin, Tang, Peiyuan, Chen, Shengzhi, Guo, Qiang, Fu, Guoxiang, Pan, Mengxue, Liang, Liping, Yao, Ye, Gao, Xiaoxue, Zhou, Yi, Zhang, Zhen, Xu, Xiaoya, Hu, Wenhuo, Gao, Jianjun, Hua, Guoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897581/
https://www.ncbi.nlm.nih.gov/pubmed/33382975
http://dx.doi.org/10.1016/j.stemcr.2020.12.005