TP53 Mutations in Acute Myeloid Leukemia: Still a Daunting Challenge?

TP53 is a key tumor suppressor gene with protean functions associated with preservation of genomic balance, including regulation of cellular senescence, apoptotic pathways, metabolism functions, and DNA repair. The vast majority of de novo acute myeloid leukemia (AML) present unaltered TP53 alleles....

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Detalles Bibliográficos
Autores principales: Molica, Matteo, Mazzone, Carla, Niscola, Pasquale, de Fabritiis, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897660/
https://www.ncbi.nlm.nih.gov/pubmed/33628731
http://dx.doi.org/10.3389/fonc.2020.610820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897660/
https://www.ncbi.nlm.nih.gov/pubmed/33628731
http://dx.doi.org/10.3389/fonc.2020.610820

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