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Trem-2 Promotes Emergence of Restorative Macrophages and Endothelial Cells During Recovery From Hepatic Tissue Damage

Macrophages are pivotal in mounting liver inflammatory and tissue repair responses upon hepatic injury, showing remarkable functional plasticity. The molecular mechanisms determining macrophage transition from inflammatory to restorative phenotypes in the damaged liver remain unclear. Using mouse mo...

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Detalles Bibliográficos
Autores principales: Coelho, Inês, Duarte, Nádia, Barros, André, Macedo, Maria Paula, Penha-Gonçalves, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897679/
https://www.ncbi.nlm.nih.gov/pubmed/33628208
http://dx.doi.org/10.3389/fimmu.2020.616044