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Safety, Tolerability, and Pharmacokinetics of Ibuprofenamine Hydrochloride Spray (NSAIDs), a New Drug for Rheumatoid Arthritis and Osteoarthritis, in Healthy Chinese Subjects

BACKGROUND: Ibuprofenamine hydrochloride spray is novel transdermal nonsteroidal anti-inflammatory drugs (NSAIDs), under clinical development for the treatment of Rheumatoid Arthritis and Osteoarthritis as a novel transdermal drug. METHODS: A single and multiple ascending dose study investigated the...

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Detalles Bibliográficos
Autores principales: Xie, Panpan, Xue, Wei, Qi, Wenyuan, Li, Yang, Yang, Lei, Yang, Zhaojun, Shi, Aixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897713/
https://www.ncbi.nlm.nih.gov/pubmed/33628011
http://dx.doi.org/10.2147/DDDT.S294849