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Patient-Specific Lymphocyte Loss Kinetics as Biomarker of Spleen Dose in Patients Undergoing Radiation Therapy for Upper Abdominal Malignancies

PURPOSE: Radiation therapy (RT)–induced lymphopenia (RIL) is linked with inferior survival in esophageal and pancreatic cancers. Previous work has demonstrated a correlation between spleen dose and RIL risk. The present study correlates spleen dose-volume parameters with fractional lymphocyte loss r...

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Detalles Bibliográficos
Autores principales: Yalamanchali, Anirudh, Zhang, Hong, Huang, Ke Colin, Mohan, Radhe, Lin, Steven H., Zhu, Cong, Grossman, Stuart A., Jin, Jian-Yue, Ellsworth, Susannah G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897770/
https://www.ncbi.nlm.nih.gov/pubmed/33665481
http://dx.doi.org/10.1016/j.adro.2020.08.002